Definition

• Thirty-two species of coagulase-negative staphylococci (CoNS) have been identified, half of them associated with human infections.
• CoNS are considerably less virulent than Staphylococcus aureus.
• Clinical syndromes
  • Prosthetic-device infections
    • S. epidermidis is the species most commonly associated with these infections.
  • Urinary tract infections (UTIs)
    • S. saprophyticus is a pathogen in UTIs among young women.
  • Native-valve endocarditis and osteomyelitis
    • Can be caused by S. lugdunensis and S. schleiferi

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