Definition

• Marburg and Ebola viruses are two distinct single-stranded RNA viruses of the family Filoviridae.
• Both viruses cause an acute febrile illness associated with high mortality.
• The illness is characterized by multisystem organ involvement that begins with abrupt headache, myalgias, and fever and proceeds to prostration, rash, and shock, often with bleeding manifestations.
• Both Marburg virus and Ebola virus are biosafety level-4 pathogens.
  
  • High mortality rate from infection
  • Aerosol infectivity (see Etiology.)
    

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