Hypoglycemia

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Prevention

  • In diabetes
    • Patient education should focus on:
      • Frequent self-monitoring of blood glucose level
      • Ensuring patient has an understanding of hypoglycemic mechanisms and precipitating factors (e.g., exercise)
      • Emphasizing the need to avoid hypoglycemia to correct hypoglycemia unawareness
      • Instruction of patient and family on treatment of severe hypoglycemia (glucagon injection)
    • Ongoing professional guidance and support
    • Flexible insulin (and other drug) regimens
    • Rational glycemic goals should balance the benefit of intensive diabetes therapy with risks of hypoglycemia.
    • Consider the use of continuous glucose monitors to evaluate for asymptomatic and/or nocturnal hypoglycemia in high-risk patients.
    • If the patient takes a beta blocker, a relatively selective β1-antagonist (e.g., metoprolol or atenolol) is preferable.
      • Nonselective beta blockers impair glycogenolysis and may attenuate recognition of hypoglycemia.
  • In critical illness
    • Maintain vigilance for hypoglycemia in patients treated with insulin infusions or patients receiving total parenteral nutrition containing insulin.

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