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Nontyphoidal Salmonellosis

Diagnostic Approach

  • Nontyphoidal Salmonella gastroenteritis is diagnosed when Salmonella is cultured from stool.
  • All salmonellae isolated in clinical laboratories should be sent to the local public health department.
  • In cases where there is concern about bacteremia (i.e., those including prolonged or recurrent fever), blood cultures are indicated.
  • If high-grade bacteremia (>50% of three or more blood cultures positive):
    • Endovascular infection is possible.
    • Further evaluation to identify a source is indicated.
  • Depending on clinical symptoms and on whether metastatic disease is suspected, other body fluids should be cultured.
    • Joint fluid
    • Cerebrospinal fluid
    • Pleural fluid

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