Harrison's Practice

Ebola and Marburg Virus Infections

Definition

  • Marburg and Ebola viruses are two distinct single-stranded RNA viruses of the family Filoviridae.
  • Both viruses cause an acute febrile illness associated with high mortality.
  • The illness is characterized by multisystem organ involvement that begins with abrupt headache, myalgias, and fever and proceeds to prostration, rash, and shock, often with bleeding manifestations.
  • Both Marburg virus and Ebola virus are biosafety level-4 pathogens.
    • High mortality rate from infection
    • Aerosol infectivity (see Etiology.)

Ebola and Marburg Virus Infections has been found in Harrison's Practice

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