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Trigeminal Neuralgia

Definition

  • Severe, paroxysmal bursts of pain in 1 or more branches of the trigeminal nerve
    • The trigeminal (fifth cranial) nerve supplies sensation to the skin of the face and anterior half of the head.
  • Sometimes known as tic douloureux

Epidemiology

  • Incidence
    • Estimated 4.5 per 100,000
  • Age
    • Primarily middle-aged and elderly
  • Sex
    • ~60% women

Risk Factors

  • Age

Etiology

  • Symptoms result from ectopic generation of action potentials in pain-sensitive afferent fibers of the fifth cranial nerve root just before it enters the lateral surface of the pons (see Figure 1).
  • Compression of the trigeminal nerve root by a blood vessel (most often the superior cerebellar artery) may be the source of neuralgia.

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