Harrison's Practice
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Shingles and Postherpetic Neuralgia

Diagnostic Procedures

  • Zoster
    • Tzanck smear
      • Tzanck smear of scraping from base of lesions to demonstrate multinucleated giant cells is rapid but has low sensitivity (~60%).
    • Cerebrospinal fluid analysis usually is not indicated unless central nervous system involvement is suspected.
      • Asymptomatic meningitis may be present.
        • Pleocytosis
        • Moderately elevated protein levels

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