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Allergic Rhinitis

Definition

  • An inflammatory condition of the nose characterized by sneezing, rhinorrhea, and obstruction of nasal passages
  • Allergic rhinitis comes in 2 varieties:
    • Seasonal allergic rhinitis related to environmental allergens present on a temporal basis
    • Perennial allergic rhinitis caused by an environment of chronic exposure
  • Vasomotor rhinitis is a distinct, nonallergic process.
    • A condition of enhanced reactivity of the nasopharynx in which a symptom complex resembling perennial allergic rhinitis occurs with nonspecific stimuli and is felt not to involve immunologic processes

Epidemiology

  • Age
    • Persons of all ages are susceptible.
    • Peaks in childhood and adolescence
    • Symptoms generally appear before 40 years of age.
  • Prevalence
    • ~20% in North America
    • ~70% of persons with asthma also experience rhinitis.
    • Up to 40% of persons with rhinitis also have asthma.
  • Incidence
    • ~7% in North America
  • Seasonal allergic rhinitis generally occurs from March through early October in North America.

Risk Factors

  • Seasonal allergic rhinitis
    • Exposure to pollens from grasses, trees, weeds, and molds
  • Perennial allergic rhinitis
    • Contact with mold spores, cockroach-derived proteins, or house dust containing mite antigens and animal danders
  • Family history
  • Personal history of collateral allergy expressed as eczematous dermatitis, urticaria, and/or asthma

Etiology

  • Nasopharyngeal entrapment of airborne pollens or other allergens results in local release of mediators that cause mucosal hyperemia, swelling, and fluid transudation.
    • In up to one-half of patients with perennial rhinitis, no definite allergen can be demonstrated as causative.
  • Food allergy is uncommon as a cause of allergic rhinitis.

Associated Conditions

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