Harrison's Practice: Cancer of the Biliary Tree

Cancer of the Biliary Tree

Definition

Cancers of the biliary tree include:
- Cancer of the gallbladder
- Cholangiocarcinoma
  - Typically refers to mucin-producing adenocarcinomas (different from hepatocellular carcinoma) that arise from the bile ducts
  - Grouped by their anatomic site of origin
    - Intrahepatic, hilar (central, ~65% of cholangiocarcinomas)
    - Peripheral (or distal, ~30% of cholangiocarcinomas)
  - Klatskin tumors: nodular tumors arising at the bifurcation of the common bile duct
- Carcinoma of the ampulla of Vater (arises within 2 cm of the distal end of the common bile duct)
  - Adenocarcinoma (90%)
  - Carcinoid tumor
  - Sarcoma

Cancer of the Biliary Tree has been found in Harrison's Practice

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